“Oz,” which is short for “ounce,” is not a valid Scrabble word. It’s also not a word in the games SOWPODS and Words With Friends, which are similar.
“Ozone” is the only five-letter word that starts with “oz.”
Still, you can use a number of two-letter words that start with “O” or “Z” in Scrabble. In fact, it would be a good idea to switch the “O” and “Z” to make “Zo.” This word can also be spelled “Dzo,” “Zho,” “Dzho,” or “Dso.” It means a Tibetan yak.
If you know these two-letter words in Scrabble, it’s easy to get a lot of points with few letters.